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程国辉，副教授，博士，硕士生导师 |
科学研究方向 |
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生物材料，肿瘤诊疗，有机聚合物 |
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联系方式 |
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电 话：0516-83262139 |
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Email：chengguohui@xzhmu.edu.cn |
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通 讯：江苏省徐州市云龙区铜山路209号，221004 |
个人简历
2015年毕业于天津医科大学药学院药学专业，获药学学士学位。2018年毕业于南开大学药学院，获得药物化学硕士学位。2021年毕业于天津大学生命科学学院，获得生物学博士学位。同年，加入徐州医科大学药学院，从事教学与科研工作。研究方向为聚合物纳米材料在生物医学方向应用。主持国家自然科学基金一项，江苏省自然科学基金一项。以第一作者或通讯作者在Advanced Materials, Nano Today，Chemical Engineering Journal，ACS Macro Letters，Journal of Colloid and Interface Science等发表论文。
承担科研课题
1. 国家自然科学基金，32201168，核交联纳米诊疗系统用于肿瘤自增强光动力治疗研究，2023.1-2025.12，30万元，项目负责人。
2. 江苏省自然科学基金，BK20220676，核交联聚合物胶束用于肿瘤自增强光动力治疗研究，2022.7-2025.6，20万元，项目负责人。
3. 江苏省“双创博士”项目资助经费，15万，项目负责人。
4. 徐州医科大学优秀人才科研启动经费，40 万元，项目负责人。
近五年代表性论文、专著
1. Guohui Cheng, Shuang Tao, Shuang Liu, Ping Wang, Chi Zhang, Jin Liu, Chuanchuan Hao, Sheng Wang*, Dong Guo*, Bo Xu*. Glutathione-Responsive Polymersome with Continuous Glutathione Depletion for Enhanced Photodynamic Therapy and Hypoxia-Activated Chemotherapy, ACS Macro Lett. 2024, 13, 599-606.
2. Ying Chen, Ziqiang Xu, Xin Wang, Xuexue Sun, Xinhui Xu, Xiao Li, and Guohui Cheng*. Highly Efficient Photodynamic Hydrogel with AIE-Active Photosensitizers toward Methicillin-Resistant Staphylococcus aureus Ultrafast Imaging and Killing, ACS Biomaterials Science & Engineering. 2024, 10(5):3401-3411.
3. Xinlu Zhang, Xu Zhang, Shutong Chen, Yongxin Liu, Chen Cao, Guohui Cheng* Sheng Wang*. Glutathione-depleting polyprodrug nanoparticle for enhanced photodynamic therapy and cascaded locoregional chemotherapy, J. Colloid Interface Sci. 2024, 670, 279-287.
4. Benshun Tian, Yuxin Wang , Wuyue Tang, Jiali Chen, Jingwen Zhang, Siyi Xue, Shaohui Zheng, Guohui Cheng* , Bing Gu* , Minghui Chen.* Tandem CRISPR nucleases-based lateral flow assay for amplification-free miRNA detection via the designed “locked RNA/DNA” as fuels, Talanta. 2024, 266:124995.
5. Guohui Cheng, Wei Zong, Haizhen Guo, Fuyan Li, Xu Zhang, Peng Yu, Fuxin Ren, Xinlu Zhang, Xiaoen Shi, Fei Gao, ⁎ Jin Chang, * Sheng Wang. * Programmed size-Changeable Nanotheranostic Agents for Enhanced Imaging-Guided Chemo/Photodynamic Combination Therapy and Fast Elimination, Advanced Materials, 2021, 33(21): 2100398.
6. Guohui Cheng, Hanjie Wang, * Chaonan Zhang, Yafeng Hao, Tiange Wang, Yingying Zhang, Yu Tian, Jin Chang.* Multifunctional nano-photosensitizer: A carrier-free aggregation-induced emission nanoparticle with efficient photosensitization and pH-responsibility, Chemical Engineering Journal, 2020, 390: 124447.
7. Guohui Cheng, Dan Wu, Sheng Wang,⁎ Xu Zhang, Peng Yu, Jin Chang,⁎ Xiaoyuan Chen.⁎ Stimuli-responsive size-changeable strategy for cancer theranostics, Nano Today, 2021, 38: 101208.
