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药剂学
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刘瑞林

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发布时间:2021年03月08日
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药剂_刘瑞林

刘瑞林,副教授,博士(),硕士生导师、博士生合作导师

科学研究方向

功能纳米多孔材料与刺激响应型水凝胶的创制及生物医学应用

联系方式

电 话:0516-83262139

Emaillrlxzmu@xzhmu.edu.cn;   lrlxjtu1987@xjtu.edu.cn

通 讯:江苏省徐州市云龙区铜山路209号,221004

个人简历

2015年毕业于陕西师范大学分析化学专业获理学博士学位,同年9月加入西安交通大学药学院任讲师、博士后研究员。20179-201910月在美国The University of Texas at Arlington从事博士后研究工作。20199月晋升为西安交通大学副教授,硕士生导师、博士生合作导师。202012月以高层次人才引进入职徐州医科大学药学院从事教学科研工作。2022年入选江苏省“333工程高层次人才培养工程”培养对象。现为中国化学会与中国生物物理学会会员,担任国家教育部研究生学位论文评审专家、陕西省科技计划项目评审专家、江苏省科技咨询专家库成员、江苏省高新技术企业认定专家库成员、广东省基础与应用基础研究基金项目评审专家、中国技术市场协会医疗器械科技创新专业委员会专家库成员。

目前主持在研江苏省自然科学基金重点研发计划项目与面上项目、徐州医科大学高层次人才科研启动基金项目和徐州市推动科技创新专项资金重点研发计划项目4项,已主持完成国家自然科学基金项目、中国博士后科学基金第11批特别资助及面上项目、中央高校基本科研业务费项目、陕西省博士后科学基金项目、陕西省自然科学基金项目以及企业横向课题等10余项。获陕西高等学校科学技术奖一等奖、陕西省科学技术奖二等奖各1项。目前科研工作主要集中于:(1)生物质/医疗固废转化先进碳基生物材料及在血液净化、生物传感、制药废水处理等领域的应用研究;(2)有机/无机杂化纳米抗菌剂的研发。

目前以第一作者或通讯作者身份在Chem. Eng. J., Nano Res., Acta Biomater., Carbon, J. Control. Release, Environ. Sci.-Nano, Bioresource Technol., Sensor. Actuat. B-Chem., Microchem. J., Microchim. Acta, Analyst, Food Chem., Food Funct., Mat. Sci. Eng.-C, J. Chromatogr. A, Anal. Chim. ActaSCI杂志发表学术论文30余篇(其中中科院SCI一区论文14篇,IF大于10SCI论文8篇),论文总被引1000余次。申报国家发明专利13项,已授权10项。参编西安交通大学留学生规划教材《Pharmaceutical Analysis》一部。受邀担任Chem. Eng. J., Carbon, J. Clean. Prod., Small, ACS Appl. Mater. Inter., Anal. Chem., Sensor. Actuat. B-Chem., Carbohyd. Polym.SCI杂志审稿人。

教学方面,主要承担临床药学专业本科生《生物药剂学》与药物制剂专业《化工原理》的课程负责人及教学工作。作为指导教师指导本科生获第十四届全国大学生药苑论坛创新成果一等奖、第九届全国大学生生命科学竞赛二等奖各1项,指导研究生获第三届江苏省大学生生物医学工程创新设计竞赛三等奖1项;指导本科生主持国家级大学生创新创业类项目(重点项目)4项,其中指导本科生以第一作者身份在Chem. Eng. J.(中科院/JCR一区Top期刊,IF 15.1)、Anal. Chim. Acta(中科院/JCR一区Top期刊,IF 5.7)与Microchem. J. (中科院二区/JCR一区Top期刊,IF 4.9) 等杂志发表学术论文4篇。

学术任职

1. 20242025年:分析化学领域英文杂志《Journal of Analysis and Testing》青年编委(Springer Nature

2. 20232025年:药学领域英文杂志《Pharmaceutical Science Advances》首届青年编委(ScienceDirect

3. 20232024年:药学领域英文杂志《Acta Materia Medica》青年编委(ScienceOpen

4. 20232026年:中国科技核心期刊《分析试验室》第二届青年编委

5. 20202022年:中国科技核心期刊《分析试验室》首届青年编委

6. 2023年~至今:化学工程领域核心期刊《Chemical Science and Engineering》编委

7. 20222023年:英文杂志《Journal of Research Updates in Polymer Science》编委

8. 20232024年:SCI杂志《MoleculesGuest EditorMDPI

9. 20202021年:SCI杂志《Frontiers in Bioengineering and BiotechnologyGuest Associate Editor

10. 2024年~至今:英文期刊《Food Safety and Health》青年编委(Wiley

主持的科研及教学课题

1.    江苏省自然科学基金(重点研发计划)项目BE20227152022.072025.0650万元,主持。

2.    江苏省自然科学基金面上项目,BK202313482023.092026.0810万元,主持。

3.    徐州市推动科技创新专项资金(重点研发计划)项目,KC21292, 2021.092023.0811万元,主持。

4.    国家自然科学基金项目,817034662018.012020.1221万元,主持。

5.    中国博士后科学基金第11批特别资助项目,2018T1110772017.112020.0515万元,主持。

6.    中国博士后科学基金面上项目,2016M5927742016.012018.125万元,主持。

7.    陕西省博士后科学基金项目,2016BSHYDZZ132016.012018.064万元,主持。

8.    陕西省自然科学基金项目2017JQ20272017.012018.113万元,主持。

9.    徐州医科大学高等教育教改课题,Xjy2022132022.112024.10,主持。

代表性论文、专著

1.      J.-J. Luo, S.-C. Zhao, D. Wu, Y.-N. Kong, C. Liu, Y.-J. Wang, X. Zhu and R.-L. Liu*. Urea-assisted fabrication of defect and oxygen vacancy-enriched Ce(MoO4)2 oxidase mimetics: A dual-mode sensor array for detection and recognition of phenolic antioxidants. Sensor. Actuat. B-Chem. 2025, 424,136922. (中科院/JCR一区, IF 8.0)

2.      J.-X. Zhou, T. Wu, Q.-Y. Ni, B.-Y. Yuan, S.-C. Zhao, Y.-Y. Sun, J. Huang, M.-L. Zou and R.-L. Liu*. A simulated sunlight-activated plastic mimic enzyme for dual-mode detection of D-penicillamine and serum iron. Microchem. J. 2024, 207, 112160. (中科院二区/JCR一区, IF 4.9)

3.      Y. Gao, J. Wang, L.-L. Zhao, B.-Y. Yuan, Y.-N. Kong, J.-J. Luo, S.-C. Zhao, W.-M. Yang and R.-L. Liu*. Biotemplated fabrication of N/O co-doped porous carbon confined spinel NiFe2O4 heterostructured mimetics for triple-mode sensing of antioxidants and ameliorating packaging properties. Food Chem. 2024, 441, 138365. (中科院/JCR一区, IF 8.5)

4.      Y. Lin, W.-W. Shao, D. Wu, T. Zhang, D.-N. Fei, Y.-N. Kong, Y.-F. Gao, S.-C. Zhao and R.-L. Liu*. Spatially confined CuFe2O4 nanosphere in N/O-codoped porous carbon mimetics for triple-mode sensing of antibiotics and visual detection of neurotransmitters in biofluids. Anal. Chim. Acta 2024, 1306, 342598. (中科院/JCR一区, IF 5.7)

5.      Y. Ge, S. Zhao, B. Yuan, Y. Gao and R. Liu*. In-situ growth of metal coordination-synergistic imprinted polymer onto shrimp shell-derived magnetic FeNi biochar for specific recognition of monocrotaline in herbal medicine. Mater. Today Sustain. 2023, 24, 100599. (中科院三区/JCR一区, IF 7.8)

6.      J. Luo, R. Liu*, S. Zhao and Y. Gao. Bimetallic Fe-Co nanoalloy confined in porous carbon skeleton with enhanced peroxidase mimetic activity for multiple biomarkers monitoring. J. Anal. Test. 2023, 7, 53-68. (中科院三区/JCR一区, IF 5.5)

7.      Y.-C. Jiang, M.-F. Luo, Z.-N. Niu, S.-Y. Xu, Y. Gao, Y. Gao, W.-J. Gao, J.-J. Luo and R.-L. Liu*. In-situ growth of bimetallic FeCo-MOF on magnetic biochar for enhanced clearance of tetracycline and fruit preservation. Chem. Eng. J. 2023, 451, 138804. (中科院/JCR一区, IF 15.1)

8.      G. Wei, Z. Wang, R. Liu*, C. Zhou, E. Li, T. Shen, X. Wang, Y. Wu and X. Li. A combination of hybrid polydopamine-human keratinocyte growth factor nanoparticles and sodium hyaluronate for the efficient prevention of postoperative abdominal adhesion formation. Acta Biomater. 2022, 138, 155-167. (中科院/JCR一区, IF 10.6)

9.      R.-L. Liu* and R.-Q. Cai. Recent advances in ultrasound-controlled fluorescence technology for deep tissue optical imaging. J. Pharm. Anal. 2022, 12(4), 530-540. (中科院/JCR一区, IF 14.026)

10.  J. Wang, S. Feng, J. Liu and R. Liu*. Effects of carboxyl or amino group modified InP/ZnS nanoparticles toward simulated lung surfactant membrane. Front. Bioeng. Biotechnol. 2021, 9, 714922. (中科院二区/JCR一区, IF 6.1)

11.  R. Liu, T. Yao, Y. Liu, S. Yu, L. Ren, Y. Hong, K.T. Nguyen and B. Yuan*. Temperature-sensitive polymeric nanogels encapsulating with β-cyclodextrin and ICG complex for high-resolution deep-tissue ultrasound-switchable fluorescence imaging. Nano Res. 2020, 13(4), 1100-1110. (中科院/JCR一区, IF 10.3)

12.  X. Xu, P. Guo, H. Shu, K. Qu, Y. Ge, G. Chen, Z. Luo, W. Du, C. Chang, R. Liu* and Q. Fu. Preparation of biocompatible molecularly imprinted film on biowaste-derived magnetic pomegranate rind carbon for protein recognition in biological sample. Mater. Sci. Eng.-C 2020, 115, 111063. (中科院二区/JCR一区, IF 8.5)

13.  Y.-H. Ge, H. Shu, X.-Y. Xu, P.-Q. Guo, R.-L. Liu*, Z.-M. Luo, C. Chang and Q. Fu. Combined magnetic porous molecularly imprinted polymers and deep eutectic solvents for efficient and selective extraction of aristolochic acid I and II from rat urine. Mater. Sci. Eng.-C 2019, 97, 650-657. (中科院二区/JCR一区, IF 8.5)

14.  Y. Wang, R.-L. Liu*, G.-N. Chen, L. Wang, P. Yu, H. Shu, K. Bashir and Q. Fu. Hemin-porous g-C3N4 hybrid nanosheets as an efficient peroxidase mimic for colorimetric and visual determination of glucose. Microchim. Acta 2019, 186(7), 446-455. (中科院二区/JCR一区, IF 6.4)

15.  H. Shu, Y. Ge, X.-Y. Xu, P.-Q. Guo, Z.-M. Luo, W. Du, C. Chang, R.-L. Liu* and Q. Fu*. Hybrid-type carbon microcoil-chitosan composite for selective extraction of aristolochic acid I from Aristolochiaceae medicinal plants. J. Chromatogr. A 2018, 1561, 13-19. (中科院二区/JCR一区)

16.  R.-L. Liu*, S. Mao, Y. Wang, L. Wang, Y.-H. Ge, X.-Y. Xu and Q. Fu. A mussel-inspired hybrid copolymer adhered to chitosan-functionalized micro-sized carbon fiber aerogels for high-efficient nanoparticles scavenging. Environ. Sci.-Nano 2017, 4, 2164-2174. (中科院/JCR一区, IF 9.5)

17.  R.-L. Liu*, P. Yu, Z.-M. Luo and Q. Fu. Multicolor fluorescent carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneous pH-responsive drug delivery and fluorescence imaging. J. Control. Release 2017, 259, 118. (中科院/JCR一区, IF 11.5)

18.  R.-L. Liu*, P. Yu, Z.-M. Luo, X.-F. Bai, X.-Q. Li and Q. Fu. Single-helix carbon microcoils prepared via Fe(Ш)-osmotically induced shape transformation of zucchini (Cucurbita pepo L.) for enhanced adsorption and antibacterial activities. Chem. Eng. J. 2017, 315, 437-447. (中科院/JCR一区, IF 15.1)

19.  R.-L. Liu*, Y. Wang, X.-L. Ge, P. Yu, H.-Q. Liu, M.-C. Wang, W. Lu, and Q. Fu. Polydopamine/polyethyleneimine complex adhered to micrometer-sized magnetic carbon fibers for high-efficiency hemoperfusion. J. Biomat. Sci.-Polym. E. 2017, 28(14), 1444-1468.  (中科院三区/JCR二区)

20.  R.-L. Liu, Z.-Q. Zhang, W.-H. Jing, L. Wang, Z.-M. Luo, R.-M. Chang, A.-G. Zeng, W. Du, C. Chang and Q. Fu. β-Cyclodextrin anchoring onto pericarpium granati-derived magnetic mesoporous carbon for selective capture of lopid in human serum and pharmaceutical wastewater samples. Mater. Sci. Eng.-C 2016, 62, 605-613. (中科院二区/JCR一区, IF 8.5)

21.  R.-L. Liu, X.-L. Ge, X.-Y. Gao, H.-Y. Zhan, T. Shi, N. Su and Z.-Q. Zhang. Two angiotensin-converting enzyme-inhibitory peptides from almond protein and the protective action on vascular endothelial function. Food & Function 2016, 7, 3733-3739. (中科院/JCR一区, IF 6.1)

22.  R.-L. Liu, W.-J. Ji, T. He, Z.-Q. Zhang*, J. Zhang and F.-Q. Dang. Fabrication of nitrogen-doped hierarchically porous carbons through a hybrid dual-template route for CO2 capture and haemoperfusion. Carbon 2014, 76, 84-95. (中科院/JCR一区, IF 10.9)

23.  R.-L. Liu, Y. Liu, X.-Y. Zhou, Z.-Q. Zhang*, J. Zhang, and F.-Q. Dang. Biomass-derived highly porous functional carbon fabricated by using a free-standing template for efficient removal of methylene blue. Bioresource Technol. 2014, 154, 138-147. (中科院/JCR一区, IF 11.4)