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吕壮，博士，讲师，硕士研究生导师 |
科学研究方向： 多吡咯类光敏剂/Ir(III), Pt(II), Ru(II)配合物光敏剂/光动力治疗/声动力治疗 |
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联系方式 |
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电 话：15050562335 |
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Email：hsyy0001@163.com |
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通 讯：江苏省徐州市云龙区铜山路209号，221004 |
个人简历
2020年08月 - 至 今 ，徐州医科大学药学院，讲师
2019年05月 - 2020年05月，香港理工大学（博士后），导师：黄维扬教授
2012年09月 - 2018年12月，南京邮电大学（博士），导师：黄维院士，赵强教授
2008年09月 - 2012年06月，河南大学（本科），导师：汪游清教授
承担科研课题
1. 江苏省基础研究计划（自然科学基金）青年项目，BK20210914，卟啉类I型光敏剂与HIF-1α抑制剂构建复合体系协同增强乏氧肿瘤光动力治疗效果研究，2021年12月至2024年12月，20万，主持。
2. 徐州医科大学引进人才启动项目，20万，主持
近五年代表性论文、专著
1. Peng Tao; Zhuang Lv（共同一作）; Fang-Qing Zhao; Xiao-Kang Zheng; He Jiang; Wentao Li; Yongjing Deng; Shujuan Liu; Guohua Xie; Wai-Yeung Wong*; Qiang Zhao*. One-Pot synthesis of acetylacetonate-based isomeric phosphorescent cyclometalated iridium (III) complexes via random cyclometalation: a strategy for excited-state manipulation. Inorganic Chemistry, 2023, 62, 1202-1209. IF: 4.6
2. Peng Tao; Zhuang Lv（共同一作）; Xiao-Kang Zheng; He Jiang; Shujuan Liu; Hua Wang; Wai-Yeung Wong*; Qiang Zhao*. Isomer engineering of lepidine-based iridophosphors for far-red hypoxia imaging and photodynamic therapy. Inorganic Chemistry, 2022, 61, 17703-17712. IF:4.6
3. Shuyi Xiao; Yufu Tang; Yimu Lin; Zhuang Lv*; Liang Chen*. In vivo nano contrast-enhanced photoacoustic imaging for dynamically lightening the molecular changes of rheumatoid arthritis. Materials & Design, 2021, 207, 109862. IF:8.4
4. Shuyi Xiao; Yufu Tang; Yimu Lin; Zhuang Lv*; Liang Chen*. Tracking osteoarthritis progress through cationic nanoprobe-enhanced photoacoustic imaging of cartilage. Acta Biomaterialia, 2020, 109, 153-162. IF:9.7
5. Zhuang Lv; Liang Zou; Huanjie Wei; Shujuan Liu; Wei Huang*; Qiang Zhao*. Phosphorescent starburst Pt(II) porphyrins as bifunctional therapeutic agents for tumor hypoxia imaging and photodynamic therapy. ACS Applied Materials & Interfaces, 2018, 10, 19523-19533. IF:9.5
6. Zhuang Lv; Huanjie Wei; Qing Li; Xianlong Su; Shujuan Liu; Kenneth Yin Zhang; Wen Lv; Qiang Zhao; Xianghong Li; Wei Huang. Achieving efficient photodynamic therapy under both normoxia and hypoxia using cyclometalated Ru (II) photosensitizer through type I photochemical process. Chemical Science, 2018, 9, 502-512. IF:8.4
7. Jiayang Jiang; Yuanyuan Qian; Zihan Xu; Zhuang Lv; Peng Tao; Mingjuan Xie; Shujuan Liu*; Wei Huang*; Qiang Zhao*. Enhancing singlet oxygen generation in semiconducting polymer nanoparticles through fluorescence resonance energy transfer for tumor treatment. Chemical Science, 2019, 10, 5085-5094. IF:8.4
8. Shuyi Xiao; Yufu Tang; Zhuang Lv; Yimu Lin; Liang Chen*. Nanomedicine-advantages for their use in rheumatoid arthritis theranostics. Journal of Controlled Release, 2019, 316, 302-316. IF:10.8
